EDTA-CaNa2 (CAS 62-33-9): Ua tiav Daim Ntawv Qhia Tus Neeg Yuav Khoom
Sau los ntawm:ALEN, Chemical Engineer, MOSINTER|15 xyoo nyob rau hauv vitamin manufacturing thiab kws APIs
Peb tus thawj tswj hwm kev yuav khoom tau hu rau kuv lub hli tas los nrog kev ntxhov siab tib yam: lawv tau nrhiavEDTA -CaNa2 (CAS 62-33-9)los ntawm cov neeg muab khoom sib txawv, tab sis batch- mus rau -batch inconsistency ua rau formulation tsis ua hauj lwm. Ib tug tau hais tias nws pab neeg tau tsis lees paub ob qhov kev xa khoom sib law liag vim tawm ntawm - cov ntsiab lus noo noo. Suab paub?
EDTA Calcium Disodium ntsev(ethylenediaminetetraacetic acid calcium disodium ntsev) yog cov hmoov dawb, tsis muaj ntxhiab crystalline hmoov uas ua haujlwm ua tus neeg sawv cev zoo heev. Nrog cov qauv molecularC10H12CaN2Na2O8, qhov sib xyaw no khi hlau ions xws li hlau, tooj liab, txhuas, thiab mercury, tiv thaiv oxidation, discoloration, thiab tawm -flavors hauv zaub mov, tshuaj pleev ib ce, thiab tshuaj siv.
Cov lus qhia no suav nrog txhua yam koj xav tau los ua qhov kev txiav txim siab yuav khoom paub meej - los ntawm cov kev qhia tshwj xeeb rau tus neeg muag khoom kev soj ntsuam uas feem ntau cov neeg yuav khoom tsis pom.
Hauv Kab Lus no
EDTA yog dab tsi -CaNa2 thiab Vim li cas CAS 62-33-9 teeb meem?
Cov ntawv thov tseem ceeb thoob plaws kev lag luam
Technical Specifications uas cuam tshuam rau kev ua tau zoo
Yuav Ntsuas Tus Neeg Siv Khoom Zoo Li Cas
Kev tswj hwm kev ua raws cai thiab kev nyab xeeb
FAQ
1. EDTA yog dab tsi-CaNa2 thiab Vim li cas CAS 62-33-9 teeb meem?
Yog tias koj tau xav paub yog vim li cas qee tus neeg xa khoom siv "CAS 62-33-9" thaum lwm tus tsuas yog hais tias "calcium EDTA," ntawm no yog qhov sib txawv uas tseem ceeb rau koj txoj kev yuav khoom.
CAS Registry Number (62-33-9) yog tus cim, thoob ntiaj teb kev lees paub rau EDTA Calcium Disodium Salt.Raws liPubChem, tus cim no ua kom koj tau txais cov tshuaj sib xyaw ua ke - tsis zoo ib yam li - suab txawv xws li disodium EDTA (CAS 139-33-3), uas muaj cov khoom sib txawv thiab kev pom zoo.
Dab tsi feem ntau cov neeg muag khoom yuav tsis qhia rau koj: cov calcium hauv EDTA-CaNa2 tsis yog ib qho kev sib tw naming xwb - nws tseem ceeb heev. Vim tias cov calcium uas twb tau chelated lawm, daim ntawv no xaiv tsuas yog cov hlau uas muaj EDTA affinity siab dua (xws li txhuas, tooj liab, thiab hlau) thaum tso cov calcium. Qhov kev xaiv no ua rau nws muaj kev nyab xeeb dua rau kev siv tshuaj uas calcium depletion yuav txaus ntshai.
Technical Properties
|
Khoom |
Specification |
|
CAS Nr |
62-33-9 |
|
EINECS Number |
200-529-9 |
|
Molecular Formula |
C10H12CaN2Na2O8 |
|
Molecular Luj |
374.27 g / mol |
|
Melting Point |
>300℃(decomposes) |
|
Boiling Point |
614.2℃ntawm 760 mmHg |
|
Qhov tshwm sim |
Dawb crystalline hmoov los yog granules |
|
Solubility (dej) |
Soluble heev |
|
pH (1% daws) |
6.5 - 7.5 |
2. Cov ntawv thov tseem ceeb thoob plaws kev lag luam
Ib tug kws tsim tshuaj pleev ib ce nyob rau hauv lub teb chaws Yelemees tsis ntev los no nug kuv vim li cas nws cov qab zib tau tig xim av tom qab peb lub hlis ntawm lub txee. Cov lus teb tau nqes mus nrhiav tooj liab ions nyob rau hauv nws cov dej reacting nrog formulation.EDTA-CaNa2 yuav tiv thaiv qhov no tag nrho los ntawm kev tshem cov hlau ions ua ntej lawv tuaj yeem ua rau oxidation.
Kev lag luam zaub mov (E385)
Hauv EU, calcium disodium EDTA nqa cov khoom noj khoom haus ntxivE385. CovTeb Chaws Asmeskas FDA (21 CFR 172.120)tso cai rau nws siv rau hauv cov khoom noj tshwj xeeb ntawm cov ntsiab lus uas tau hais tseg. Cov ntawv thov tseem ceeb suav nrog:
Cov zaub hauv kaus poom:Tiv thaiv kom tsis muaj xim nyob rau hauv legumes, nceb (txog 365 ppm)
Mayonnaise thiab zaub xam lav:Khaws qhov tshiab, tiv thaiv rancidity (75-100 ppm)
Carbonated dej haus:Khaws tsw, txo turbidity
Cov kaus poom nqaij nruab deg:Tiv thaiv struvite crystal tsim hauv cw (250 ppm)
Kev siv tshuaj
EDTA-CaNa2 yog FDA- pom zoo rau kev kho mob hnyav hlau lom, tshwj xeeb tshaj yog cov tshuaj toxicity.Tsis zoo li disodium EDTA, daim ntawv calcium tsis deplete lub cev cov khw muag khoom calcium, ua rau nws zoo dua rau kev siv lub cev. Nws yog marketed nyob rau hauv lub npe zoo liCalcium Disodium Versenatehauv chaw kho mob.
Tshuaj pleev ib ce thiab kho tus kheej
Nyob rau hauv cov tshuaj pleev ib ce, ntsej muag cream, thiab xab npum, EDTA-CaNa2 ua raws li tus neeg sawv cev chelating uas txhim kho cov khoom ruaj khov thiab txuas lub neej txee. Los ntawm kev khi cov kab hlau los ntawm dej thiab lwm cov khoom xyaw, nws tiv thaiv oxidative degradation ntawm cov khoom siv sib txuas thiab tswj xyuas cov khoom ua tau zoo.
|
Kev lag luam |
Lub luag haujlwm tseem ceeb |
Hom Concentration |
|
Khoom noj khoom haus (cov kaus poom) |
Xim tuav, antioxidant |
75-365 ppm |
|
Dej haus |
Flavour stability, clarity |
25-33 ppm |
|
Tshuaj |
Hnyav hlau detoxification |
Raws li tshuaj |
|
Tshuaj pleev ib ce |
Kev ruaj ntseg, ruaj khov |
0.1-1.0% |
|
Kev lag luam |
Hlau ion tswj |
Daim ntawv thov - tshwj xeeb |
3. Technical Specifications uas cuam tshuam rau kev ua tau zoo
Nov yog qhov kuv tau kawm los ntawm 15 xyoo ntawm kev ua haujlwm nrog cov neeg ua haujlwm chelating: Daim ntawv pov thawj ntawm Kev Ntsuam Xyuas (CoA) cov lej uas pab pawg muag khoom feem ntau tsom rau - purity thiab hnyav hlau - tsis yog qhov tseem ceeb tshaj plaws rau koj daim ntawv thov.
FDA xav kom muaj tsawg kawg yog 99% purity rau zaub mov-qib calcium disodium EDTA (xws li dihydrate lossis trihydrate form).Txawm li cas los xij, rau kev siv tshuaj, koj yuav xav txheeb xyuas USP lossis EP ua raws, uas suav nrog kev sim ntxiv rau kev txwv microbial thiab cov impurities tshwj xeeb.
Parameters Tsim nyog sib tham
Cov ntsiab lus noo noo yog qhov ntsiag to killer ntawm batch sib xws. Cov ntaub ntawv dihydrate thiab trihydrate muaj cov ntsiab lus dej sib txawv, uas cuam tshuam rau kev sib cais thiab kev ua haujlwm zoo. Yog tias koj cov formulation yog rhiab heev rau cov dej ua haujlwm, qhia meej tias daim ntawv hydrate koj xav tau thiab teeb tsa cov dej noo nruj dua li tus qauv.
|
Parameter |
Qib zaub mov |
Pharma Qib (USP) |
|
Purity |
Ntau dua lossis sib npaug li 99.0% |
Ntau dua lossis sib npaug li 99.0% |
|
Heavy Metals (Pb) |
<10 ppm |
<10 ppm |
|
Arsenic |
<3 ppm |
<1.5 ppm |
|
Poob rau ziab |
Qhia tus nqi |
Qhia ntau yam |
|
Microbial txwv |
Tsis xav tau |
Yuav tsum tau |
4. Yuav ntsuas tus neeg muab khoom zoo li cas
Tom qab tshuaj xyuas ntau dua 200 tus neeg muag khoom tshawb xyuas hauv kuv txoj haujlwm, kuv tau pom tus qauv: cov lus nug feem ntau cov neeg yuav khoomtsis txhobnug feem ntau yog cov uas tseem ceeb tshaj plaws.
Tshaj li cov ntawv pov thawj, nug cov neeg muag khoom txog lawv qhov kev xeem batch zaus, cov khoom siv raw, thiab seb lawv puas tuaj yeem muab cov ntaub ntawv ruaj khov.Ib tus neeg muag khoom uas tsim khoom hauv - lub tsev feem ntau yuav muaj kev sib raug zoo dua li tus tub luam uas tau txais los ntawm ntau lub hoobkas.
Red Chij Saib Kom Paub
CoA cov hnub uas tsis phim cov hnub tsim khoom
Tsis kam muab cov qauv khaws cia
Tus nqi uas qis dua qhov nruab nrab ntawm kev ua lag luam (feem ntau qhia tau hais tias cov shortcuts zoo)
Tsis muaj lus teb meej txog qhov chaw tsim khoom
Yuav Thov Li Cas
Ua ntej - cov qauv xa khoom xa tuaj rau koj tus kheej kev kuaj xyuas
Thib peb-cov ntaub ntawv qhia chaw kuaj (tsis yog cov chaw tsim khoom CoA)
ISO 9001 lossis GMP cov ntaub ntawv pov thawj
Cov ntaub ntawv keeb kwm batch qhia qhov sib xws ntawm lub sijhawm
5. Kev Ua Raws Cai thiab Kev Nyab Xeeb
Kev nkag siab txog kev tswj hwm thaj chaw tsis yog hais txog kev ua raws cai - nws yog hais txog kev paub txog kev lag luam twg koj cov khoom tuaj yeem nkag mus.
Calcium disodium EDTA tau pom zoo ua zaub mov ntxiv los ntawm FDA thiab EU (E385).CovEFSAtau tsim ib qho Kev Tau Txais Txhua Hnub (ADI) ntawm 0-2.5 mg / kg lub cev qhov hnyav, thaum FDA tso cai siv txog qhov txwv tshwj xeeb hauv cov khoom noj uas tau xaiv.
Kev ruaj ntseg Profile
EDTA-CaNa2 muaj qhov zoo-cov ntaub ntawv kev nyab xeeb. Tsuas yog 2-5% ntawm qhov ncauj noj calcium disodium EDTA yog absorbed hauv plab hnyuv; cov seem yog excreted unchanged. Qhov bioavailability qis no pab txhawb rau nws cov txiaj ntsig kev nyab xeeb hauv kev siv zaub mov. Yog xav paub ntxiv txog cov ntaub ntawv toxicological, xa mus rauPubChem database nkag.
|
Kev tswj lub cev |
xwm txheej |
|
FDA (USA) |
Pom zoo - 21 CFR 172.120 |
|
EFSA (EU) |
Pom zoo - E385 |
|
JECFA (WHO/FAO) |
ADI: 0-2.5 mg/kg bw |
|
Halal Status |
Muaj ntawv pov thawj Halal |
|
Kosher Status |
Kosher Pareve |
Cov lus nug nquag
Puas yog EDTA-CaNa2 zoo ib yam li disodium EDTA?
Tsis yog. Thaum ob qho tib si yog EDTA derivatives, calcium disodium EDTA (CAS 62-33-9) muaj chelated calcium ion, ua rau nws muaj kev nyab xeeb rau cov ntawv thov uas calcium depletion yuav muaj teeb meem. Disodium EDTA (CAS 139-33-3) tuaj yeem khi calcium los ntawm lub cev thiab tsis tuaj yeem hloov pauv hauv kev siv tshuaj.
Dab tsi yog qhov kev txiav txim yam tsawg kawg nkaus rau EDTA ntau -CaNa2?
Feem ntau cov tuam ntxhab, suav nrog MOSINTER, muaj qhov tsawg kawg nkaus ntawm 10 metric tons rau kev xa khoom ntau. Rau qhov me me, kev txiav txim mus sib yuav muaj raws li qhov kev thov. Lub sij hawm txhuas feem ntau yog 7 hnub rau cov qauv specifications.
Puas yog calcium disodium EDTA vegan thiab gluten -dawb?
Yog lawm. EDTA-CaNa2 yog tsim los ntawm cov pob zeb hauv av (tsis yog tsiaj- muab tau los) thiab tsis muaj gluten. Nws tsim nyog rau cov neeg tsis noj nqaij, neeg tsis noj nqaij, thiab celiac- cov qauv tsim ua phooj ywg.
EDTA -CaNa2 yuav tsum khaws cia li cas?
Khaws rau hauv qhov chaw txias, qhuav kom deb ntawm tshav ntuj ncaj qha. Txawm hais tias qhov sib xyaw ua ke ruaj khov nyob rau hauv ib txwm muaj, cov av noo ntau dhau tuaj yeem cuam tshuam rau lub xeev hydration. Kev khaws cia kom zoo, txee lub neej feem ntau tshaj 24 lub hlis.
EDTA -CaNa2 puas tuaj yeem hloov kho rau cov ntawv thov tshwj xeeb?
Yog lawm. Cov tuam txhab muaj npe nrov tuaj yeem kho qhov me me, daim ntawv hydration, thiab purity specifications raws li koj daim ntawv thov. Cov kev xaiv ntim kev cai kuj feem ntau muaj.
Xaus
Xaiv txoj cai EDTA-CaNa2 tus neeg muag khoom ncaj qha cuam tshuam rau koj cov qauv kev sib xws, kev tswj hwm kev cai, thiab thaum kawg, koj qhov kawg - khoom zoo. Nrog 21 xyoo ntawm kev tsim khoom thiab kev tsim khoom muaj peev xwm ntawm 50,000 tons ib xyoos ib zaug, MOSINTER xa cov batch - rau -batch sib xws uas cov neeg tsim khoom loj xav tau.
Npaj los tham txog koj EDTA-CaNa2 cov cai?
Hu rau peb pab neeg ua haujlwm rau kev qhia tshwj xeeb, qauv, thiab tus nqi sib tw.
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