Vitamin B1 (Thiamine Chloride) yog dab tsi? Ua tiav Phau Ntawv Qhia

Vitamin B1 (Thiamine Chloride) yog dab tsi? Ua tiav Phau Ntawv Qhia

Sau los ntawm: ALEN, Chemical Engineer, MOSINTER|15 xyoo nyob rau hauv vitamin manufacturing thiab kws APIs

Ob lub lis piam dhau los, tus kws tshuaj tshuaj los ntawm lub teb chaws Yelemees tau hu rau cov lus nug ceev: "Peb tau sim peb qhov sib txawv ntawm cov vitamin B1, thiab qhov purity txawv ntawm 96% mus rau 99.5%. Vim li cas qhov sib txawv no?" Qhov no scenario plays tawm ntau zaus hauv kuv inbox. Qhov tsis meej pem nyob ib ncig ntawm thiamine cov kev qhia tshwj xeeb zoo ua rau cov pab pawg muaj txiaj ntsig rau lub sijhawm thiab, qhov tseem ceeb tshaj, tuaj yeem cuam tshuam qhov kawg - cov khoom lag luam.

Vitamin B1, tseem hu ua Thiamine Chloride (CAS 59-}43-8), yog ib qho tseem ceeb hauv dej-soluble vitamin uas ua lub luag haujlwm tseem ceeb hauv carbohydrate metabolism thiab lub paj hlwb ua haujlwm.Nrog molecular formula C₁₂H₁₇ClN₄OS thiab molecular hnyav ntawm 300.81 g / mol, cov hmoov dawb crystalline no tshwm nyob rau ntau qhov kev lag luam -los ntawm kev tsim tshuaj mus rau kev tsim khoom noj khoom haus thiab khoom noj khoom haus tsiaj. Raws liNIH's Office of Dietary Supplements, thiamine yog metabolically nquag ua haujlwm li thiamine pyrophosphate (TPP), ua haujlwm ua coenzyme hauv decarboxylation ntawm -keto acids. Kev nkag siab txog cov hauv paus ntsiab lus no pab cov neeg yuav khoom txiav txim siab txog kev tsim khoom.

Cov Lus Qhia

Vitamin B1 yog dab tsi thiab nws ua haujlwm li cas?

Key Specifications thiab Quality Parameters

Muaj kev siv ntawm Thiamine Chloride

Yuav ntsuas cov vitamin B1 tus neeg muab khoom zoo li cas

FAQ: Cov lus nug ntau txog Vitamin B1

Vitamin B1 yog dab tsi thiab nws ua haujlwm li cas?

Ib tus kws tshawb fawb txog zaub mov tsis ntev los no nug kuv tias vim li cas qee cov tshuaj B1 yaj sai dua lwm tus. Cov lus teb yog nyob rau hauv kev nkag siab txog thiamine lub cim molecular qauv thiab nws tus cwj pwm nyob rau hauv ntau yam mob.

Thiamine chloride muaj hloov pauv pyrimidine thiab thiazole rings txuas los ntawm tus choj methylene. Cov qauv tshwj xeeb no ua rau nws muaj dej ntau heev -soluble tab sis rhiab rau cov cua sov thiab alkaline tej yam kev mob.Lub compound muaj nyob rau hauv ntau yam interconvertible phosphorylated daim ntawv, nrog thiamine pyrophosphate (TPP) yog thawj active daim ntawv. Thaum raug kub siab tshaj 100℃los yog pH qib siab tshaj 7, thiamine pib degrade-ib qho tseem ceeb rau cov formulators ua hauj lwm nrog kub- cov khoom ua tiav.

Raws li cov ntaub ntawv los ntawmPubChem (CID 1130), thiamine ua haujlwm raws li coenzyme koom nrog ntau yam tseem ceeb hauv cov txheej txheem metabolic:

Decarboxylation ntawm -keto acids hauv carbohydrate metabolism

Kev tsim hluav taws xob los ntawm lub voj voog citric acid (TCA).

Nerve impulse kis tau tus mob thiab nqaij contraction

Ceg -chain amino acid metabolism

Acetylcholine synthesis rau kev txawj ntse muaj nuj nqi

Lub cev tsis tuaj yeem tsim cov thiamine, ua rau kev noj zaub mov kom tsawg lossis ntxiv cov khoom tseem ceeb. Tsis zoo li cov rog- cov vitamins soluble, thiamine tsis tuaj yeem khaws cia rau hauv cov nyiaj tseem ceeb - ntau dhau raug tso tawm los ntawm cov zis hauv teev. Qhov kev hloov pauv sai no piav qhia tias vim li cas kev noj zaub mov zoo ib hnub tseem ceeb rau kev tswj hwm qib siab.

Vitamin B1 Basic Parameters

Key Specifications thiab Quality Parameters

"Yuav ua li cas cov neeg muag khoom feem ntau yuav tsis qhia rau koj" yog qhov kev kuaj purity sib txawv ntawm cov chaw kuaj mob. Ib pawg uas qhia txog 99% purity nyob rau hauv HPLC tsom xam yuav sau npe tsuas yog 97% raws li txoj kev titration. Nov yog qhov tseem ceeb thaum ntsuas B1 zoo rau koj daim ntawv thov tshwj xeeb.

Pharmaceutical- qib Vitamin B1 yuav tsum ua tau raws li USP / EP cov qauv nrog purity Ntau dua lossis sib npaug li 99.0%, cov dej noo tsawg dua lossis sib npaug li 5.0%, thiab cov hlau hnyav tsawg dua lossis sib npaug li 10 ppm.CovChemSpider databaselees paub cov cim zoo tseem ceeb uas paub qhov txawv tshuaj -qib los ntawm pub- qib khoom. Tshaj li tus lej purity, cov qib residual hnyav, microbial suav, thiab particle loj faib cuam tshuam kev ua tau zoo.

Hauv kuv qhov kev tshuaj xyuas tus neeg xa khoom COAs, peb qhov tsis tsim nyog yuav tsum tau ua tib zoo mloog: Ua ntej, txheeb xyuas cov txheej txheem ntsuas qhov sib npaug ntawm koj cov txheej txheem QC. Thib ob, tshawb xyuas cov khoom hnyav uas seem- nce qib acetone lossis ethanol qhia tias qhuav tsis tiav. Thib peb, tshuaj xyuas microbial kuaj rau TAMC / TYMC suav, tshwj xeeb tshaj yog tseem ceeb rau cov ntawv sau qhov ncauj.

Qib Qib Kev Sib Piv

Muaj kev siv ntawm Thiamine Chloride

Peb lub hlis dhau los, peb tau xa cov Vitamin B1 mus rau 47 daim ntawv thov sib txawv thoob plaws 12 lub teb chaws. Lub versatility ntawm thiamine chloride tseem ua rau xav tsis thoob txawm tias cov qub tub rog cov kws ua haujlwm tshuaj. Los ntawm txhaj tshuaj vitamin daws rau tsiaj cov khoom noj premixes, daim ntawv thov spectrum txuas ntxiv.

Thiamine chloride cov ntawv thov tseem ceeb tshaj tawm cov tshuaj APIs, cov kev pab txhawb nqa zaub mov, cov khoom noj khoom haus, thiab cov khoom noj tsiaj ntxiv.Raws li covNCBI Bookshelf ntawm Vitamin B1, thiamine yog FDA- pom zoo rau kev kho Wernicke encephalopathy, infantile beriberi, thiab kab mob plawv uas tshwm sim los ntawm thiamine deficiency. Cov chaw muag tshuaj ib leeg suav txog kwv yees li 35% ntawm kev xav tau thiamine thoob ntiaj teb.

Cov cheeb tsam thov tseem ceeb

Pharmaceutical Manufacturing:API rau vitamin B complex formulations, txhaj tshuaj, ntsiav tshuaj qhov ncauj, thiab multivitamin npaj. Thiamine hydrochloride yog qhov zoo dua rau kev siv parenteral vim nws qhov kev ruaj ntseg zoo dua hauv kev daws teeb meem.

Food Fortification:Ntxiv cov hmoov nplej, nplej, cereals, thiab cov qauv me nyuam mos raws li WHO thiab FDA cov lus qhia. Yuav tsum muaj kev tiv thaiv kev tiv thaiv hauv 80+ lub teb chaws tau txo qis qhov tshwm sim ntawm beriberi.

Khoom noj khoom haus ntxiv:Khoom noj khoom haus, dej haus, thiab khoom noj khoom haus kev ua si. Kev loj hlob ntawm cov neeg siv khoom xav tau kev xav tau siab -potency B- cov qauv tsim.

Tsiaj Noj Khoom Noj:Pub premixes rau nqaij qaib, swine, aquaculture, thiab tus khub tsiaj. Thiamine deficiency hauv cov ntses ua rau cov tsos mob neurological thiab kev tuag.

Kev Kho Mob:Kev tswj xyuas kev kho mob ntawm beriberi, Wernicke-Korsakoff syndrome, thiab thiamine- teb tus kab mob maple syrup zis.

Pom zoo noj txhua hnub (raws li NIH Cov Lus Qhia)

Yuav ntsuas cov vitamin B1 tus neeg muab khoom zoo li cas

Tom qab 15 xyoo nrhiav cov khoom siv vitamin raw khoom, kuv tau tsim ib daim ntawv tshuaj xyuas uas cais cov tuam txhab lag luam txhim khu kev qha los ntawm cov tub lag luam tsuas yog flipping cov khoom. Qhov sib txawv feem ntau qhia txog rau lub hlis tom qab thaum muaj teeb meem tsis sib xws, lossis phem dua, thaum lub sij hawm soj ntsuam xyuas.

Ib tus neeg tsim nyog Vitamin B1 yuav tsum ua kom pom ISO 9001/ISO 22000 daim ntawv pov thawj, muab ntau yam sib xws - rau - ntau cov ntaub ntawv COA, tuav DMF (Drug Master File) rau npe rau daim ntawv thov tshuaj, thiab muab kev txhawb nqa rau kev tsim cov nyom.Tus nqi yuav tsum tsis txhob yog tus txheej txheem xaiv ib leeg xwb- qhov ua tsis tau zoo raug nqi ntau dua li kev txuag nyiaj los ntawm cov khoom pheej yig.

Supplier Evaluation Checklist

MOSINTER coj 21 xyoo kev paub hauv kev tsim cov tshuaj vitamin. Peb qhov chaw tsim khoom tswj hwm GMP ntawv pov thawj nrog txhua xyoo muaj peev xwm tshaj 30 tons. Peb muab cov ntaub ntawv tag nrho suav nrog COA, MSDS, thiab kev tswj hwm kev txhawb nqa rau kev lag luam thoob ntiaj teb. Mus ntsib pebKhoom noj khoom haus additivesnploojrau peb cov khoom lag luam vitamin tiav, lossis tshawb xyuas pebPharmaceutical Chemicals API catalograu tshuaj- cov ntaub ntawv qib. Peb pab neeg teb rau cov lus nug hauv 24 teev.

FAQ: Cov lus nug ntau txog Vitamin B1

Dab tsi yog qhov txawv ntawm thiamine thiab vitamin B1?

Thiamine thiab Vitamin B1 yog tib yam sib xyaws -thiamine yog lub npe tshawb fawb, thaum Vitamin B1 yog lub npe siv hauv cov khoom siv.Thiamine chloride (CAS 59-43-8) thiab thiamine mononitrate (CAS 532-43-4) yog ob hom kev lag luam tshaj plaws. Chloride muaj cov dej solubility zoo dua, ua rau nws zoo tagnrho rau cov kua formulations thiab txhaj tshuaj. Mononitrate muab kev ruaj ntseg zoo dua hauv cov ntawv thov qhuav xws li kev tsim cov ntsiav tshuaj thiab hmoov nplej fortification.

Kuv yuav tsum noj vitamin B1 ntau npaum li cas txhua hnub?

Qhov pom zoo pub nyiaj txhua hnub yog 1.2 mg rau cov txiv neej laus thiab 1.1 mg rau cov poj niam laus.Cov poj niam cev xeeb tub thiab lactating xav tau 1.4 mg ib hnub twg los txhawb kev loj hlob ntawm fetus thiab kev tsim cov kua mis. Lub koom haum WHO pom zoo 10 mg ib hnub rau kev kho mob me me, nrog rau koob tshuaj txog 50-100 mg rau cov mob hnyav hauv kev saib xyuas kev kho mob. Cov neeg ncaws pob thiab cov tib neeg uas muaj cov carbohydrates ntau tuaj yeem tau txais txiaj ntsig los ntawm kev ntxiv ntau dua.

Koj puas tuaj yeem noj ntau cov vitamin B1?

Tsis Muaj Kev Tiv Thaiv Qib Siab Siab (UL) tau tsim los rau thiamine vim tias cov nyiaj ntau dhau tau tawm sai sai los ntawm cov zis.Cov dej-soluble yam ntawm thiamine ua rau toxicity tsawg heev. Txawm li cas los xij, kev siv tshuaj ntau dhau (ntau dua 50 mg) tuaj yeem ua rau muaj kev mob tshwm sim me me nrog rau kev tawm ntawm daim tawv nqaij, khaus, lossis tsis xis nyob hauv plab hauv qee tus neeg. Nco ntsoov sab laj nrog kws kho mob ua ntej noj cov tshuaj - ntau npaum li cas, tshwj xeeb tshaj yog cov mob uas twb muaj lawm.

Cov zaub mov twg muaj vitamin B1 siab?

Cov khoom muaj txiaj ntsig zoo suav nrog cov nplej tag nrho, nqaij npuas (tshwj xeeb yog cov nqaij ntshiv), nqaij qaib, taum pauv, taum dub, txiv ntseej (tshwj xeeb yog macadamia thiab noob paj noob hlis), thiab legumes.Cov khoom noj muaj zog nrog rau cov qhob cij ntxiv, cov zaub mov, nplej zom, thiab mov muab thiamine tseem ceeb hauv Western cov zaub mov. Kev ua noj poob tuaj yeem ncav cuag 25-40%, yog li cov zaub mov nyoos lossis ua tiav tsawg kawg xa cov nyiaj bioavailable ntau dua. Cov kev pab cuam fortification muaj cai nyob rau hauv ntau tshaj 80 lub teb chaws tau txo cov pej xeem-theem deficiency.

Cov tsos mob ntawm vitamin B1 deficiency yog dab tsi?

Cov tsos mob thaum ntxov muaj xws li qaug zog, khaus khaus, tsis nco qab, txo qis qab los noj mov, pw tsaug zog, thiab cov leeg tsis muaj zog.Kev loj hlob tsis txaus ua rau beriberi- tshwm sim raws li peripheral neuropathy (tingling, kub hnyiab hauv extremities), cov tsos mob ntawm cov hlab plawv (lub plawv loj, tachycardia), thiab teeb meem plab hnyuv. Cov mob hnyav tshwm sim rau hauv Wernicke-Korsakoff syndrome, uas muaj kev tsis meej pem, nco tsis tau, thiab teeb meem kev sib koom tes. Kev haus dej cawv ntev ntev tseem yog qhov ua rau muaj ntau tshaj plaws hauv cov teb chaws uas muaj kev lag luam vim yog qhov tsis zoo ntawm kev nqus thiab cov khw muag khoom siab.

Xaus

Vitamin B1 (Thiamine Chloride, CAS 59-43-8) tseem yog qhov tseem ceeb ntawm kev lag luam kws tshuaj, zaub mov, thiab tsiaj txhu kev lag luam. Xaiv cov qib zoo thiab tus neeg muag khoom ncaj qha cuam tshuam rau koj cov khoom zoo thiab kev tswj hwm kev ua raws cai. Txawm hais tias kev nrhiav khoom ntxiv rau kev tsim khoom, kev tsim khoom noj khoom haus, lossis kev siv tsiaj txhu, saib xyuas cov neeg muag khoom tseem ceeb uas qhia tau zoo ib yam, cov ntaub ntawv qhia meej, thiab kev txawj ntse tiag tiag.

Npaj txhij los muab cov tshuaj - qib Vitamin B1?Hu rau MOSINTER hnub no rau tus nqi sib tw, COA cov ntaub ntawv, qauv muaj, thiab kev txhawb nqa kev txhawb nqa. Yam tsawg kawg nkaus xaj: 1 KG. Lub sij hawm xa tuaj: 7 hnub.

Tiv tauj peb:

WhatsApp pawg:+8618989305995

Email:info1@mosinterchem.com

Lub Vev Xaib:www.moschemical.com